A new paradigm for designing ring construction strategies for green organic synthesis: implications for the discovery of multicomponent reactions to build molecules containing a single ring

• John Andraos

Beilstein J. Org. Chem. 2016, 12, 2420–2442, doi:10.3762/bjoc.12.236

• economy; green organic synthesis; integer partitioning; reactions; probability; retrosynthetic analysis; ring construction strategy; Introduction The ring motif is a key feature in chemical structures that has long attracted the attention of synthetic organic chemists in their quest to implement novel

• of ring construction strategy from a very different perspective that is rooted in an entirely different scientific field which also has enjoyed an even longer track record of research, namely combinatorics and enumeration. Specifically, we exploit the subject of integer partitioning [123][124][125